Bucky wrote:yep, that is the notion that is saving my sanity right now.
generally true, but not exactly. phase 2 trials are too small to see safety effects in small populations. phase III isn't only an effectiveness trial. hell, sometimes drugs have to be taken off market after they pass trials because of unacceptable side effects in some subpops that they couldn't detect...or because of long lasting effects like cancer (though obviously this wouldnt be caught in a phase 3). also phase IIs are generally health populations.jamiethekiller wrote:two both points:
we've seen that anytime Trump pushes something it get SUCH a large backlash that it won't get the credit it may deserve. There is nothing that Trump can do that the left/center will accept as correct. All vaccines that are viable are into phase 3 trials and that means that they're safe to consume. They may have some bad side effects, but overall, they're pretty safe. If the Vaccine that gets pushed out is effective, but the majority of the population refuses to take it becaue they don't trust that Trump made the correct judgement call, then it'll be disastorous for the public. I think the FDA is only looking for 50% efficacy for the vaccine and doesn't require USA results for it(brazila or SA results would work).
JUburton wrote:generally true, but not exactly. phase 2 trials are too small to see safety effects in small populations. phase III isn't only an effectiveness trial. hell, sometimes drugs have to be taken off market after they pass trials because of unacceptable side effects in some subpops that they couldn't detect...or because of long lasting effects like cancer (though obviously this wouldnt be caught in a phase 3). also phase IIs are generally health populations.jamiethekiller wrote:two both points:
we've seen that anytime Trump pushes something it get SUCH a large backlash that it won't get the credit it may deserve. There is nothing that Trump can do that the left/center will accept as correct. All vaccines that are viable are into phase 3 trials and that means that they're safe to consume. They may have some bad side effects, but overall, they're pretty safe. If the Vaccine that gets pushed out is effective, but the majority of the population refuses to take it becaue they don't trust that Trump made the correct judgement call, then it'll be disastorous for the public. I think the FDA is only looking for 50% efficacy for the vaccine and doesn't require USA results for it(brazila or SA results would work).
you're right on 50% effectiveness...its fairly low but probably makes sense for an early vaccine.
this is going to be a mess no matter what becuase its never been done on a scale like this, with public trust in vaccines (bad) and the admin (with good reason) at an all time low. and this vaccine seems like it actually can knock you on your ass for a day or two.
i know you said to others but i'd probably look at how it was approved here first. was it standard approval process, was it the FDA head, HHS head with increasing skepticism as it goes up the chain. no matter what i'd probably wait for some 3rd party reviews of the paper that accompanies it (as im sure this will exist). it won't be patient level access or anything but should give a pretty clear indication on risk. it would be even better if the EMA approves it also.jamiethekiller wrote:JUburton wrote:generally true, but not exactly. phase 2 trials are too small to see safety effects in small populations. phase III isn't only an effectiveness trial. hell, sometimes drugs have to be taken off market after they pass trials because of unacceptable side effects in some subpops that they couldn't detect...or because of long lasting effects like cancer (though obviously this wouldnt be caught in a phase 3). also phase IIs are generally health populations.jamiethekiller wrote:two both points:
we've seen that anytime Trump pushes something it get SUCH a large backlash that it won't get the credit it may deserve. There is nothing that Trump can do that the left/center will accept as correct. All vaccines that are viable are into phase 3 trials and that means that they're safe to consume. They may have some bad side effects, but overall, they're pretty safe. If the Vaccine that gets pushed out is effective, but the majority of the population refuses to take it becaue they don't trust that Trump made the correct judgement call, then it'll be disastorous for the public. I think the FDA is only looking for 50% efficacy for the vaccine and doesn't require USA results for it(brazila or SA results would work).
you're right on 50% effectiveness...its fairly low but probably makes sense for an early vaccine.
this is going to be a mess no matter what becuase its never been done on a scale like this, with public trust in vaccines (bad) and the admin (with good reason) at an all time low. and this vaccine seems like it actually can knock you on your ass for a day or two.
Thanks for the clarifications.
to others: Would you take the same vaccine thats approved in UK in october, but not approved by the FDA in october? Woudl you take the vaccine that Trump pushed in October at the end of November?
heyeaglefn wrote:TenuredVulture wrote:Trump pushing to get a vaccine distributed in late October is in my opinion likely to backfire. It seems much of his base are likely anti-vaxxers, and I would bet that an overwhelming majority of the 30% who say they would refuse a vaccine are Trump supporters. I mean, sure, some Trump supporters did drink the bleach (I think bleach should replace kool-aid as the beverage of choice for the gullible) but I think many will stop at actually injecting something into their bodies. Non-Trump supporters don't trust him anyway.
I don't think trump needs to worry about the part of his base that are anti-vaxxers, he has their votes anyway. It isn't the uneducated, anti mask wearers he needs to swing, he has their vote.
He needs to try to work on some of the undecided college educated voters that trust scientists.
jamiethekiller wrote:JUburton wrote:generally true, but not exactly. phase 2 trials are too small to see safety effects in small populations. phase III isn't only an effectiveness trial. hell, sometimes drugs have to be taken off market after they pass trials because of unacceptable side effects in some subpops that they couldn't detect...or because of long lasting effects like cancer (though obviously this wouldnt be caught in a phase 3). also phase IIs are generally health populations.jamiethekiller wrote:two both points:
we've seen that anytime Trump pushes something it get SUCH a large backlash that it won't get the credit it may deserve. There is nothing that Trump can do that the left/center will accept as correct. All vaccines that are viable are into phase 3 trials and that means that they're safe to consume. They may have some bad side effects, but overall, they're pretty safe. If the Vaccine that gets pushed out is effective, but the majority of the population refuses to take it becaue they don't trust that Trump made the correct judgement call, then it'll be disastorous for the public. I think the FDA is only looking for 50% efficacy for the vaccine and doesn't require USA results for it(brazila or SA results would work).
you're right on 50% effectiveness...its fairly low but probably makes sense for an early vaccine.
this is going to be a mess no matter what becuase its never been done on a scale like this, with public trust in vaccines (bad) and the admin (with good reason) at an all time low. and this vaccine seems like it actually can knock you on your ass for a day or two.
Thanks for the clarifications.
to others: Would you take the same vaccine thats approved in UK in october, but not approved by the FDA in october? Woudl you take the vaccine that Trump pushed in October at the end of November?
jamiethekiller wrote:JUburton wrote:generally true, but not exactly. phase 2 trials are too small to see safety effects in small populations. phase III isn't only an effectiveness trial. hell, sometimes drugs have to be taken off market after they pass trials because of unacceptable side effects in some subpops that they couldn't detect...or because of long lasting effects like cancer (though obviously this wouldnt be caught in a phase 3). also phase IIs are generally health populations.jamiethekiller wrote:two both points:
we've seen that anytime Trump pushes something it get SUCH a large backlash that it won't get the credit it may deserve. There is nothing that Trump can do that the left/center will accept as correct. All vaccines that are viable are into phase 3 trials and that means that they're safe to consume. They may have some bad side effects, but overall, they're pretty safe. If the Vaccine that gets pushed out is effective, but the majority of the population refuses to take it becaue they don't trust that Trump made the correct judgement call, then it'll be disastorous for the public. I think the FDA is only looking for 50% efficacy for the vaccine and doesn't require USA results for it(brazila or SA results would work).
you're right on 50% effectiveness...its fairly low but probably makes sense for an early vaccine.
this is going to be a mess no matter what becuase its never been done on a scale like this, with public trust in vaccines (bad) and the admin (with good reason) at an all time low. and this vaccine seems like it actually can knock you on your ass for a day or two.
Thanks for the clarifications.
to others: Would you take the same vaccine thats approved in UK in october, but not approved by the FDA in october? Woudl you take the vaccine that Trump pushed in October at the end of November?
Stay_Disappointed wrote:Approval for a vaccine definitely dropping on Nov 2
jamiethekiller wrote:piece: please don't put words in my mouth, i think the admin has screwed up just about everything from the start. I'm just curious about what people would do if a vaccine thats approved based on UK/SA other country results was 'rushed' through the FDA process. There's going to be results in another month or two that are based off of other countries population responses. JU can fact check me, but i think the two best candidates are much further along in other countries than the US. Also curious where people stand on taking a rushed vaccine a month or two later after release. I thought JU had a good response on waiting for more peer review reports to come out. Which, like i said, could end up being a disaster if the vaccine was actually effective(for all the reasons stated by TV and others).
I'm not sure i'd get the vaccine(or even allowed to get it), but i'd certainly hope that all my older/elderly family were able to get it as soon as it was allowable.
azrider wrote:shit, i thought this stuff only happened to left-center liberals like myself on BSG.
https://medium.com/the-forgotten-generation/submit-for-ultraliberal-reconditioning-d8b474ff36af
good read and oh so true, well at least the majority.